This week, Johnson & Johnson is expected to ask the FDA to approve a booster for its one-shot COVID-19 vaccine. So far, the FDA has authorized Pfizer’s BioNTech vaccination for a third booster in specific groups: those over 65, persons at high risk of severe disease, immunocompromised individuals, and frontline healthcare workers. The CDC now includes people between 18 and 64 who are at increased risk because of their employment or living circumstances.